Compound Q&A
How is (1S,2S,3S,5S)-5-[2-Amino-6-(benzyloxy)-9H-purin-9-yl]-3-(benzyloxy)-2-[(benzyloxy)methyl]cyclopentanol (CAS: 142217-77-4) typically synthesized?
Answer
![(1S,2S,3S,5S)-5-[2-Amino-6-(benzyloxy)-9H-purin-9-yl]-3-(benzyloxy)-2-[(benzyloxy)methyl]cyclopentanol](https://static.chemtradehub.com/structs/142/142217-77-4-f297.webp "(1S,2S,3S,5S)-5-[2-Amino-6-(benzyloxy)-9H-purin-9-yl]-3-(benzyloxy)-2-[(benzyloxy)methyl]cyclopentanol")
This compound is synthesized through multistep reactions involving purine derivatives and cyclopentanol. Common methods include Grignard reactions and Suzuki coupling, using catalysts like Pd(0) and ligands. Yields are typically high, around 70-80%, with good regioselectivity.
About
CAS No
142217-77-4
English Name
(1S,2S,3S,5S)-5-[2-Amino-6-(benzyloxy)-9H-purin-9-yl]-3-(benzyloxy)-2-[(benzyloxy)methyl]cyclopentanol
Molecular Formula
C32H33N5O4
Molecular Weight
551.6470000000004 g/mol
SMILES
C1C(C(C(C1OCC2=CC=CC=C2)COCC3=CC=CC=C3)O)N4C=NC5=C4N=C(N=C5OCC6=CC=CC=C6)N
InChIKey
SYPCZZWUNIHLBU-COROXYKFSA-N
Last Updated: 2025-09-13 09:53
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