Compound Q&A

How is (1S,2S,3R,4S,6R)-4,6-Diamino-3-({(2R,3R,6S)-3-amino-6-[(1S)-1-(methylamino)ethyl]tetrahydro-2H-pyran-2-yl}oxy)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside (CAS: 1403-66-3) typically synthesized?

Answer

(1S,2S,3R,4S,6R)-4,6-Diamino-3-({(2R,3R,6S)-3-amino-6-[(1S)-1-(methylamino)ethyl]tetrahydro-2H-pyran-2-yl}oxy)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside
This compound is synthesized through multiple steps, typically involving condensation reactions, amidation, and protection/deprotection steps using appropriate catalysts. The synthesis requires careful control of reaction conditions to achieve high yield and selectivity. Commonly used solvents include dichloromethane (DCM) and acetonitrile, and the reaction is often carried out under anhydrous conditions to prevent side reactions.

About

CAS No 1403-66-3
English Name (1S,2S,3R,4S,6R)-4,6-Diamino-3-({(2R,3R,6S)-3-amino-6-[(1S)-1-(methylamino)ethyl]tetrahydro-2H-pyran-2-yl}oxy)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside
Molecular Formula C21H43N5O7
Molecular Weight 477.6 g/mol
EINECS 215-765-8
SMILES CC([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)NC
InChIKey CEAZRRDELHUEMR-URQXQFDESA-N
Last Updated: 2025-09-13 09:53

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