Compound Q&A

How is 4-Dodecylphenol (CAS: 27193-86-8) typically synthesized?

Answer

4-Dodecylphenol
4-Dodecylphenol (CAS: 27193-86-8) is typically synthesized via the Grignard reaction, where phenol reacts with dodecyllithium. The reaction is carried out in anhydrous ether or THF in the presence of a phase-transfer catalyst to enhance the reaction rate. The product is then isolated and purified by recrystallization. This method provides good yield and selectivity, making it a suitable approach for industrial production.

About

CAS No 27193-86-8
English Name 4-Dodecylphenol
Molecular Formula C36H60O2
Molecular Weight 524.87 g/mol
EINECS 248-312-8
SMILES CCCCCCCCCCCCc1ccccc1O.CCCCCCCCCCCCc1ccc(cc1)O
InChIKey LLTWLSZALYFVDM-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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