Compound Q&A
How is Nafarelin (CAS: 76932-56-4) typically synthesized?
Answer
Nafarelin is synthesized through a multi-step process involving peptide coupling reactions and protection/deprotection steps. Commonly, the synthesis involves the use of Fmoc (9-fluorenylmethoxycarbonyl) protection for the amino groups, followed by coupling with the appropriate amino acid residues. The final product is then deprotected and purified using high-performance liquid chromatography (HPLC).
About
CAS No
76932-56-4
English Name
Nafarelin
Molecular Formula
C66H83N17O13
Molecular Weight
1322.5 g/mol
SMILES
CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)C(CC2=CC3=CC=CC=C3C=C2)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7)NC(=O)C8CCC(=O)N8
InChIKey
RWHUEXWOYVBUCI-ITQXDASVSA-N
Last Updated: 2025-09-13 09:53