Compound Q&A
How is Rifamycin O (CAS: 14487-05-9) typically synthesized?
Answer
Rifamycin O is typically synthesized through a multi-step process involving fermentation and chemical modification. The fermentation step involves the production of the natural precursor, followed by chemical modifications such as acetylation and demethylation to yield Rifamycin O. Common catalysts and reagents include acetic anhydride and sodium methoxide. The overall yield is around 30-40%, with high selectivity for the desired product.
About
CAS No
14487-05-9
English Name
Rifamycin O
Molecular Formula
C39H47NO14
Molecular Weight
753.8 g/mol
SMILES
CC1C=CC=C(C(=O)NC2=CC3(C4=C(C2=O)C(=C(C5=C4C(=O)C(O5)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)OCC(=O)O3)C
InChIKey
RAFHKEAPVIWLJC-KQOHHTLASA-N
Last Updated: 2025-09-13 09:53
