Compound Q&A

How is 2-Aminoimidazole (CAS: 7720-39-0) typically synthesized?

Answer

2-Aminoimidazole
2-Aminoimidazole is often synthesized via the condensation of acetamide and malononitrile in the presence of a base like sodium hydroxide. The reaction involves the elimination of cyanide to form the imidazole ring, followed by the substitution of the nitrile group with an amino group. The yield is typically around 70-80%, and the selectivity is high for the desired product.

About

CAS No 7720-39-0
English Name 2-Aminoimidazole
Molecular Formula C3H5N3
Molecular Weight 83.09 g/mol
SMILES C1=CN=C(N1)N
InChIKey DEPDDPLQZYCHOH-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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