Compound Q&A

How is (3-Methylphenyl)acetic acid (CAS: 621-36-3) typically synthesized?

Answer

(3-Methylphenyl)acetic acid
The synthesis of (3-Methylphenyl)acetic acid is typically achieved via the reaction of 3-methylbenzyl chloride with sodium acetate in an aqueous medium. This method provides good yield and selectivity. Other synthetic routes include the reduction of 3-methylbenzoyl chloride with sodium borohydride or the coupling of 3-methylbenzaldehyde with acetic acid. These methods are widely used due to their simplicity and efficiency.

About

CAS No 621-36-3
English Name (3-Methylphenyl)acetic acid
Molecular Formula C9H10O2
Molecular Weight 150.18 g/mol
SMILES CC1=CC(=CC=C1)CC(=O)O
InChIKey GJMPSRSMBJLKKB-UHFFFAOYSA-N
Last Updated: 2025-09-13 09:53

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