How is Pivalonitrile (CAS: 630-18-2) typically synthesized?

Pivalonitrile is typically synthesized by the reaction of pivaloyl chloride with sodium hydroxide in an aprotic solvent such as acetonitrile. The process involves the nucleophilic substitution of the chloride ion by the hydroxide ion, followed by deprotonation to form the nitrile. This reaction is conducted under anhydrous conditions to prevent hydrolysis and requires careful control of pH and temperature to achieve high selectivity and yield.