Compound Q&A

How is 2-Chloro-4-fluoro-5-nitrophenol (CAS: 84478-75-1) typically synthesized?

Answer

2-Chloro-4-fluoro-5-nitrophenol
2-Chloro-4-fluoro-5-nitrophenol (CAS: 84478-75-1) can be synthesized through a multistep process involving the nitration of 4-fluoro-5-chlorophenol, followed by chlorination of the nitro derivative. This reaction typically requires strong acids such as sulfuric acid and high temperatures. The process is highly selective and yields up to 90% purity, depending on the reaction conditions and purification methods.

About

CAS No 84478-75-1
English Name 2-Chloro-4-fluoro-5-nitrophenol
Molecular Formula C6H3ClFNO3
Molecular Weight 191.5443 g/mol
SMILES OC1=CC([N+]([O-])=O)=C(F)C=C1Cl
InChIKey NAWVMCKMQMJQMF-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15

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