Compound Q&A
How is (2Z)-2-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-1,3-thiazol-4-yl]-2-pentenoic acid (CAS: 86978-24-7) typically synthesized?
Answer
![(2Z)-2-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-1,3-thiazol-4-yl]-2-pentenoic acid](https://static.chemtradehub.com/structs/869/86978-24-7-a0df.webp "(2Z)-2-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-1,3-thiazol-4-yl]-2-pentenoic acid")
(2Z)-2-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-1,3-thiazol-4-yl]-2-pentenoic acid is usually synthesized via a multi-step process involving the protection of the amino group, followed by coupling with the 1,3-thiazole derivative, and subsequent deprotection. Commonly used catalysts include palladium(II) acetate and triphenylphosphine, with a yield of around 75%.
About
CAS No
86978-24-7
English Name
(2Z)-2-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-1,3-thiazol-4-yl]-2-pentenoic acid
Molecular Formula
C13H18N2O4S
Molecular Weight
298.36 g/mol
SMILES
CC/C=C(C1=CSC(NC(OC(C)(C)C)=O)=N1)\C(O)=O
InChIKey
XIXNSLABECPEMI-VURMDHGXSA-N
Last Updated: 2025-09-10 15:15
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