Compound Q&A

How is (1S,5S)-6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane (CAS: 18172-67-3) typically synthesized?

Answer

(1S,5S)-6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane
(1S,5S)-6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane (CAS: 18172-67-3) can be synthesized via Wittig olefination of 2,6-dimethylcyclohexanone with methyltriphenylphosphonium bromide. The reaction typically proceeds with a high yield and good selectivity, and the product can be isolated by recrystallization from ethanol.

About

CAS No 18172-67-3
English Name (1S,5S)-6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane
Molecular Formula C10H16
Molecular Weight 136.24 g/mol
SMILES C=C1CC[C@H]2C[C@@H]1C2(C)C
InChIKey WTARULDDTDQWMU-IUCAKERBSA-N
Last Updated: 2025-09-09 19:18

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