Compound Q&A

How is 4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione (CAS: 77168-63-9) typically synthesized?

Answer

4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione
4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione can be synthesized via the thiocondensation of 4-pyridyl mercaptan with thiosemicarbazide. The reaction typically requires basic conditions and is carried out in solvents such as ethanol or methanol. The yield is generally around 70-80%, and the product can be isolated by recrystallization from an appropriate solvent.

About

CAS No 77168-63-9
English Name 4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione
Molecular Formula C8H6N2S2
Molecular Weight 194.28 g/mol
SMILES C1=CN=CC=C1C2=CSC(=S)N2
InChIKey LEQNUYXXLYRUNY-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

Related Q&A

Compound Q&A

What are the physical and chemical properties of 4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione (CAS: 77168-63-9)?

4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione has a crystalline form and a molecular weight of approxima...

Compound Q&A

What industries use 4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione (CAS: 77168-63-9)?

4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione is used in various industries. It finds applications in ph...

Compound Q&A

What precautions should be taken when handling 4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione (CAS: 77168-63-9)?

When handling 4-(4-Pyridinyl)-1,3-thiazole-2(3H)-thione, it is important to wear appropriate persona...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...