Compound Q&A

How is 2-(Trifluoromethyl)acrylic acid (CAS: 381-98-6) typically synthesized?

Answer

2-(Trifluoromethyl)acrylic acid
2-(Trifluoromethyl)acrylic acid is typically synthesized via the reaction of trifluoromethyl acetyl chloride with sodium methoxide. This process yields a 90% yield of the desired product with high structural integrity. The reaction is conducted under mild conditions to ensure selectivity and purity.

About

CAS No 381-98-6
English Name 2-(Trifluoromethyl)acrylic acid
Molecular Formula C4H3F3O2
Molecular Weight 140.06 g/mol
SMILES C=C(C(=O)O)C(F)(F)F
InChIKey VLSRKCIBHNJFHA-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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