Compound Q&A

How is (E)-N-(3-(3-(dimethylamino)acryloyl)phenyl)-N-ethylacetamide (CAS: 96605-66-2) typically synthesized?

Answer

(E)-N-(3-(3-(dimethylamino)acryloyl)phenyl)-N-ethylacetamide
(E)-N-(3-(3-(dimethylamino)acryloyl)phenyl)-N-ethylacetamide is synthesized via a multi-step process. The initial step involves the preparation of 3-(dimethylamino)acrylic acid, which is then reacted with phenylacetylene to form the key intermediate. This intermediate is further reacted with ethyl acetamide in the presence of a suitable base to yield the final product. This synthesis typically requires mild conditions and can achieve good yields.

About

CAS No 96605-66-2
English Name (E)-N-(3-(3-(dimethylamino)acryloyl)phenyl)-N-ethylacetamide
Molecular Formula C15H20N2O2
Molecular Weight 260.33 g/mol
SMILES CCN(C1=CC=CC(=C1)C(=O)C=CN(C)C)C(=O)C
InChIKey UXWJJVRASIHSQS-MDZDMXLPSA-N
Last Updated: 2025-09-09 19:18

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