Compound Q&A
How is 2-Chloro-1H-benzimidazole (CAS: 4857-06-1) typically synthesized?
Answer
2-Chloro-1H-benzimidazole (CAS: 4857-06-1) is commonly synthesized via the reaction of 1,3-dichlorobenzene with hydrazine hydrate. This process involves heating the mixture to around 140°C under an atmosphere of nitrogen. The product can then be purified by recrystallization from ethanol. This synthesis method provides good yield and selectivity.
About
CAS No
4857-06-1
English Name
2-Chloro-1H-benzimidazole
Molecular Formula
C7H5ClN2
Molecular Weight
152.58 g/mol
SMILES
C1=CC=C2C(=C1)NC(=N2)Cl
InChIKey
AYPSHJCKSDNETA-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18
