Compound Q&A

How is Diethyl 1,1-cyclobutanedicarboxylate (CAS: 3779-29-1) typically synthesized?

Answer

Diethyl 1,1-cyclobutanedicarboxylate
Diethyl 1,1-cyclobutanedicarboxylate (CAS: 3779-29-1) is typically synthesized from 1,1-cyclobutanedicarboxylic acid and diethylamine. The reaction involves the substitution of the carboxylic acid groups with ethyl esters. This process often uses a mild base like triethylamine as a catalyst. The reaction is highly selective and yields up to 95% of the desired product. The yield can be improved by optimizing reaction conditions such as temperature and concentration.

About

CAS No 3779-29-1
English Name Diethyl 1,1-cyclobutanedicarboxylate
Molecular Formula C10H16O4
Molecular Weight 200.23 g/mol
SMILES CCOC(=O)C1(CCC1)C(=O)OCC
InChIKey JPNJEJSZSMXWSV-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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