Compound Q&A
How is Methyl 5-chloro-2-pyrazinecarboxylate (CAS: 33332-25-1) typically synthesized?
Answer
Methyl 5-chloro-2-pyrazinecarboxylate (CAS: 33332-25-1) can be synthesized by the condensation of chloroacetyl chloride with 2-pyrazinecarboxaldehyde in the presence of a suitable base like sodium carbonate. This reaction is typically carried out in an aprotic solvent such as dimethylformamide (DMF) at room temperature. The yield of the product is around 75-80%, and the reaction is known for its good selectivity, making it a reliable method for industrial production.
About
CAS No
33332-25-1
English Name
Methyl 5-chloro-2-pyrazinecarboxylate
Molecular Formula
C6H5ClN2O2
Molecular Weight
172.57 g/mol
SMILES
COC(=O)C1=CN=C(C=N1)Cl
InChIKey
CVVMLRFXZPKILB-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18
