Compound Q&A

How is (R)-2-(oleoyloxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate (CAS: 26853-31-6) typically synthesized?

Answer

(R)-2-(oleoyloxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
(R)-2-(Oleoyloxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate is synthesized through a series of reactions involving transesterification and phosphorylation steps. The compound is typically prepared using a combination of oleic acid, palmitic acid, and trimethylamine as starting materials. The synthesis involves careful control of pH and temperature to achieve high yield and selectivity.

About

CAS No 26853-31-6
English Name (R)-2-(oleoyloxy)-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
Molecular Formula C42H82NO8P
Molecular Weight 760.1 g/mol
SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC
InChIKey WTJKGGKOPKCXLL-VYOBOKEXSA-N
Last Updated: 2025-09-09 19:18

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