Compound Q&A

How is (2,6-Difluorophenyl)acetic acid (CAS: 85068-28-6) typically synthesized?

Answer

(2,6-Difluorophenyl)acetic acid
(2,6-Difluorophenyl)acetic acid is often synthesized via the acetylation of 2,6-difluorophenol using acetic anhydride in the presence of a catalyst such as sulfuric acid. The reaction yields the desired compound with good selectivity and moderate to high yield, depending on the purification method.

About

CAS No 85068-28-6
English Name (2,6-Difluorophenyl)acetic acid
Molecular Formula C8H6F2O2
Molecular Weight 172.13 g/mol
SMILES OC(=O)Cc1c(F)cccc1F
InChIKey FUGDCKXBUZFEON-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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