Compound Q&A

How is (S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (CAS: 608141-43-1) typically synthesized?

Answer

(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (S)-2-acetamido-4-methylpentanoate
(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (CAS: 608141-43-1) can be synthesized via a multi-step approach involving the protection of a phenolic hydroxyl group, subsequent amidation, and desilylation. This process typically yields a product with good selectivity and high yield. Commonly, triphenylphosphine and triethylamine are used as catalysts in the amidation step.

About

English Name (S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (S)-2-acetamido-4-methylpentanoate
Molecular Formula C20H34N2O7S
Molecular Weight 446.57 g/mol
SMILES CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N)OC.CC(C)CC(C(=O)O)NC(=O)C
InChIKey KJZXYHPZWRDLAR-JIJBYVMQSA-N
Last Updated: 2025-09-09 19:18

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