Compound Q&A

How is Ethyl 4-iodobenzoate (CAS: 51934-41-9) typically synthesized?

Answer

Ethyl 4-iodobenzoate
Ethyl 4-iodobenzoate is typically synthesized through the reaction of 4-hydroxybenzoic acid with sodium iodide in the presence of an organic base such as triethylamine. The reaction is conducted in an organic solvent like ethanol or acetonitrile. The yield is generally high, and the reaction is known for its good selectivity towards iodination.

About

CAS No 51934-41-9
English Name Ethyl 4-iodobenzoate
Molecular Formula C9H9IO2
Molecular Weight 276.07 g/mol
SMILES CCOC(=O)C1=CC=C(C=C1)I
InChIKey YCBJOQUNPLTBGG-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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