Compound Q&A
How is 2-Chloro-5-fluorobenzyl Bromide (CAS: 81778-09-8) typically synthesized?
Answer
2-Chloro-5-fluorobenzyl Bromide is typically synthesized through the reaction of 2-chloro-5-fluorobenzyl alcohol with phosphorus tribromide in the presence of a suitable base like potassium hydroxide. The reaction is carried out in an inert solvent such as diethyl ether. This method provides good yield and selectivity, making it a common industrial synthesis route.
About
CAS No
81778-09-8
English Name
2-Chloro-5-fluorobenzyl Bromide
Molecular Formula
C7H5BrClF
Molecular Weight
223.47 g/mol
SMILES
C1=CC(=C(C=C1F)CBr)Cl
InChIKey
AUVLFQDKJFSFIX-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06
