Compound Q&A
How is Aliskiren hemifumarate (CAS: 173334-58-2) typically synthesized?
Answer
Aliskiren hemifumarate (CAS: 173334-58-2) is synthesized via a multi-step process involving the condensation of aliskiren with fumaric acid hemifumarate. The reaction typically uses acetic anhydride as a condensing agent and occurs under moderate temperature and pressure conditions. The yield is around 90%, and the method is known for its high selectivity and good purity.
About
CAS No
173334-58-2
English Name
Aliskiren hemifumarate
Molecular Formula
C64H110N6O16
Molecular Weight
1219.6099999999994 g/mol
SMILES
CC(C)C(CC1=CC(=C(C=C1)OC)OCCCOC)CC(C(CC(C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.CC(C)C(CC1=CC(=C(C=C1)OC)OCCCOC)CC(C(CC(C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=CC(=O)O)C(=O)O
InChIKey
KLRSDBSKUSSCGU-ZRHJJGBDSA-N
Last Updated: 2025-09-09 08:06
