Compound Q&A

How is (5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-(2-thienylmethylene)-beta-D-glucopyranoside (CAS: 29767-20-2) typically synthesized?

Answer

(5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-(2-thienylmethylene)-beta-D-glucopyranoside
The compound is typically synthesized through a multistep process involving the protection of the hydroxyl groups, followed by ring-opening reactions, and finally, the glycosylation step. Commonly used catalysts include Lewis acids, and the overall yield is moderate. The synthetic route involves protecting reagents and careful control of reaction conditions to ensure high selectivity.

About

CAS No 29767-20-2
English Name (5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-(2-thienylmethylene)-beta-D-glucopyranoside
Molecular Formula C32H32O13S
Molecular Weight 656.662 g/mol
SMILES COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)OC6C(C(C7C(O6)COC(O7)C8=CC=CS8)O)O
InChIKey NRUKOCRGYNPUPR-PSZSYXFXSA-N
Last Updated: 2025-09-09 08:06

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