Compound Q&A

How is 2-(Diphenylphosphino)benzaldehyde (CAS: 50777-76-9) typically synthesized?

Answer

2-(Diphenylphosphino)benzaldehyde
2-(Diphenylphosphino)benzaldehyde (CAS: 50777-76-9) is commonly synthesized through the reaction of benzaldehyde with phosphorus tribromide in the presence of a base like sodium hydroxide. The reaction involves the formation of a phosphonium salt intermediate, followed by reduction to the desired aldehyde. The yield is typically around 70-80%, with good selectivity towards the target product.

About

CAS No 50777-76-9
English Name 2-(Diphenylphosphino)benzaldehyde
Molecular Formula C19H15OP
Molecular Weight 290.3 g/mol
SMILES C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3C=O
InChIKey DRCPJRZHAJMWOU-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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