Compound Q&A

How is 1H-Pyrazole-4-carboxylic acid (CAS: 37718-11-9) typically synthesized?

Answer

1H-Pyrazole-4-carboxylic acid
1H-Pyrazole-4-carboxylic acid can be synthesized via a multi-step route starting from 2-bromo-1H-pyrazole or other precursors. Common methods include the condensation of 2-bromo-1H-pyrazole with carboxylic acids or the reduction of 1H-pyrazole-4-carboxaldehyde. The synthesis often uses conditions such as sodium hydride or sodium borohydride as reducing agents, and the process yields can range from 50% to 75%, depending on the specific reaction conditions and purity of starting materials.

About

CAS No 37718-11-9
English Name 1H-Pyrazole-4-carboxylic acid
Molecular Formula C4H4N2O2
Molecular Weight 112.09 g/mol
SMILES C1=C(C=NN1)C(=O)O
InChIKey IMBBXSASDSZJSX-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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