Compound Q&A
How is 2,5-Dimethyl-1H-indole (CAS: 1196-79-8) typically synthesized?
Answer
2,5-Dimethyl-1H-indole is commonly synthesized via the Biginelli reaction, which involves the condensation of acetic anhydride, urea, and 2,5-dimethylfuran. The reaction requires a catalyst like p-toluenesulfonic acid and typically yields 70-80% of the product. The indole ring is formed through a cyclization and condensation process.
About
CAS No
1196-79-8
English Name
2,5-Dimethyl-1H-indole
Molecular Formula
C10H11N
Molecular Weight
145.2 g/mol
SMILES
CC1=CC2=C(C=C1)NC(=C2)C
InChIKey
ZFLFWZRPMDXJCW-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06
