Compound Q&A
How is Josamycin (CAS: 16846-24-5) typically synthesized?
Answer
Josamycin (CAS: 16846-24-5) is typically synthesized through a semi-synthetic process involving modifications to the natural compound tylosin. The synthesis involves a series of chemical reactions, including acetylation, reduction, and epoxidation. Commonly used catalysts include metal complexes, and the overall yield can range from 50% to 70%. The process is selective and aims to preserve the macrolide ring structure, which is crucial for its biological activity.
About
CAS No
16846-24-5
English Name
Josamycin
Molecular Formula
C42H69NO15
Molecular Weight
828 g/mol
SMILES
CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)OC(=O)C)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O)C)O
InChIKey
XJSFLOJWULLJQS-NGVXBBESSA-N
Last Updated: 2025-09-09 08:06
