Compound Q&A

How is (2S,3R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate (CAS: 93635-76-8) typically synthesized?

Answer

(2S,3R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate
(2S,3R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate can be synthesized via a multistep process involving the reaction of 2,2-dimethyl-1,3-dioxane-4-carbaldehyde with ethyl alcohol in the presence of sodium hydroxide. The yield is typically around 75%, and the reaction is highly selective for the desired stereochemistry.

About

CAS No 93635-76-8
English Name (2S,3R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-methylpropanoate
Molecular Formula C11H20O6
Molecular Weight 248.27499999999998 g/mol
SMILES CCOC(=O)C(C)(C(C1COC(O1)(C)C)O)O
InChIKey BHCHXRCKXIVVCN-XLDPMVHQSA-N
Last Updated: 2025-09-09 08:06

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