Compound Q&A

How is 2-Ethylpyrazine (CAS: 13925-00-3) typically synthesized?

Answer

2-Ethylpyrazine
2-Ethylpyrazine is usually synthesized by the condensation of ethylamine and pyrazine-2-carboxylic acid or its derivatives. Commonly, amines and carboxylic acids undergo a coupling reaction in the presence of a catalyst like titanium tetrachloride. The yield is typically around 70-80%, with good selectivity towards the desired product.

About

CAS No 13925-00-3
English Name 2-Ethylpyrazine
Molecular Formula C6H8N2
Molecular Weight 108.14 g/mol
SMILES CCc1cnccn1
InChIKey KVFIJIWMDBAGDP-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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