Compound Q&A

How is 3-Thienylacetic acid (CAS: 6964-21-2) typically synthesized?

Answer

3-Thienylacetic acid
3-Thienylacetic acid can be synthesized via the condensation of 2-thienylacetonitrile with sodium hydroxide or by the reaction of thienylacetic anhydride with a suitable base. Common catalysts include sodium hydroxide and potassium hydroxide. The yield is typically around 75-85%, and high selectivity is achieved under mild conditions.

About

CAS No 6964-21-2
English Name 3-Thienylacetic acid
Molecular Formula C6H6O2S
Molecular Weight 142.179 g/mol
SMILES C1=CSC=C1CC(=O)O
InChIKey RCNOGGGBSSVMAS-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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