Compound Q&A

How is 2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide (CAS: 51218-49-6) typically synthesized?

Answer

2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide
2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide (CAS: 51218-49-6) is typically synthesized via a multi-step process involving the reaction of 2-chloroacetyl chloride with 2,6-diethylphenylamine and 2-propoxyethanol. The synthesis involves a condensation reaction followed by an electrophilic aromatic substitution, yielding the desired product in moderate to good yield. Common catalysts include triethylamine and other basic reagents.

About

CAS No 51218-49-6
English Name 2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide
Molecular Formula C17H26ClNO2
Molecular Weight 311.85 g/mol
SMILES CCCOCCN(C1=C(C=CC=C1CC)CC)C(=O)CCl
InChIKey YLPGTOIOYRQOHV-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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