What regulatory guidelines apply to 1H-Benzimidazole-5-carboxylic acid (CAS: 15788-16-6)?

1H-Benzimidazole-5-carboxylic acid (CAS: 15788-16-6) is regulated under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) as a hazardous chemical. In Europe, it falls under REACH regulations, which require manufacturers and importers to register substances if they have a tonnage threshold of one ton per year. For the U.S., the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) have specific regulations concerning its use and handling in pharmaceuticals and consumer products.