Compound Q&A
How is (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one (CAS: 42399-49-5) typically synthesized?
Answer
(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is typically synthesized via a multi-step process starting from 4-methoxyaniline and 2-bromo-3-hydroxybenzothiazole. The synthesis involves nucleophilic substitution, followed by condensation and cyclization reactions. Commonly used catalysts include potassium carbonate and molecular sieves. The overall yield is around 75-80%.
About
CAS No
42399-49-5
English Name
(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
Molecular Formula
C16H15NO3S
Molecular Weight
301.37 g/mol
SMILES
COc1ccc(cc1)[C@@H]2Sc3ccccc3NC(=O)[C@@H]2O
InChIKey
LHBHZALHFIQJGJ-CABCVRRESA-N
Last Updated: 2025-09-08 00:42
