Compound Q&A

How is 4-(Methylthio)benzaldehyde (CAS: 3446-89-7) typically synthesized?

Answer

4-(Methylthio)benzaldehyde
4-(Methylthio)benzaldehyde is commonly synthesized via the reaction of methyl mercaptan with benzaldehyde. The reaction typically proceeds via a nucleophilic substitution at the benzaldehyde aldehyde group. Other methods include the reduction of 4-methylthioacetophenone with sodium borohydride. The yield is usually around 80-85%, and the method involves the use of a milder catalyst for better selectivity.

About

CAS No 3446-89-7
English Name 4-(Methylthio)benzaldehyde
Molecular Formula C8H8OS
Molecular Weight 152.22 g/mol
SMILES CSC1=CC=C(C=C1)C=O
InChIKey QRVYABWJVXXOTN-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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