Compound Q&A
How is Bendamustine USP Related Compound C (CAS: 3543-74-6) typically synthesized?
Answer
Bendamustine USP Related Compound C (CAS: 3543-74-6) is synthesized via a multi-step process involving the condensation of 4-chlorobenzoic acid and 2-chloro-1,3-dimethyl-2,3-dihydro-1H-indol-3-one, followed by esterification and cyclization. This synthesis typically uses catalytic amounts of acetic anhydride and a dehydrating agent like phosphorus oxychloride, with high selectivity and yield.
About
CAS No
3543-74-6
English Name
Bendamustine USP Related Compound C
Molecular Formula
C18H27N3O4
Molecular Weight
349.4 g/mol
SMILES
CCOC(=O)CCCC1=NC2=C(N1C)C=CC(=C2)N(CCO)CCO
InChIKey
SJYOJVBTSZGDQH-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
