Compound Q&A

How is 2-Chloro-1,3-benzoxazole (CAS: 615-18-9) typically synthesized?

Answer

2-Chloro-1,3-benzoxazole
2-Chloro-1,3-benzoxazole (CAS: 615-18-9) is commonly synthesized by the condensation of 3-chlorobenzaldehyde with oxamide. The process involves heating the mixture under reflux to promote the formation of the oxazole ring. Other methods include the reaction of benzoyl chloride with chlorobenzene in the presence of a base, yielding a high yield of the product.

About

CAS No 615-18-9
English Name 2-Chloro-1,3-benzoxazole
Molecular Formula C7H4ClNO
Molecular Weight 153.56799999999996 g/mol
SMILES C1=CC=C2C(=C1)N=C(O2)Cl
InChIKey BBVQDWDBTWSGHQ-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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