Compound Q&A

How is Baloxavir Marboxil (CAS: 1985606-14-1) typically synthesized?

Answer

Baloxavir Marboxil
Baloxavir Marboxil is synthesized through a multi-step路线,包括酰胺化、酯交换和还原反应。关键步骤涉及使用二异丙基乙胺作为催化剂,在无水无氧条件下进行反应。总收率约为80%,产物通过HPLC和NMR进行纯度和结构确认。

About

English Name Baloxavir Marboxil
Molecular Formula C27H23F2N3O7S
Molecular Weight 571.56 g/mol
SMILES COC(=O)OCOc1c2C(=O)N3CCOC[C@H]3N([C@H]4c5ccc(F)c(F)c5CSc6ccccc46)n2ccc1=O
InChIKey RZVPBGBYGMDSBG-GGAORHGYSA-N
Last Updated: 2025-09-08 00:42

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