Compound Q&A
How is (2-Methoxy-5-pyrimidinyl)boronic acid (CAS: 628692-15-9) typically synthesized?
Answer
(2-Methoxy-5-pyrimidinyl)boronic acid is commonly synthesized via the reaction of 2-methoxy-5-pyrimidone with triphenylphosphine borate. This process involves the use of a catalyst such as tetrakis(triphenylphosphine)palladium(0) and a base like triethylamine. The reaction is carried out under mild conditions, and the yield can be up to 80%. This synthetic method provides a reliable route to this compound for various applications.
About
CAS No
628692-15-9
English Name
(2-Methoxy-5-pyrimidinyl)boronic acid
Molecular Formula
C5H7BN2O3
Molecular Weight
153.93 g/mol
SMILES
B(C1=CN=C(N=C1)OC)(O)O
InChIKey
YPWAJLGHACDYQS-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
