Compound Q&A
How is Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate octahydrate (CAS: 81028-91-3) typically synthesized?
Answer
Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate octahydrate is synthesized through a multi-step process involving the reaction of a suitable diol with phosphorus oxychloride followed by neutralization with sodium hydroxide. Commonly used catalysts include triethylamine. The overall process yields high purity product with good selectivity and yields.
About
CAS No
81028-91-3
English Name
Sodium (3S,4R,5R)-6-((hydrogenphosphonato)oxy)-3,4,5-trihydroxy-2-oxohexyl phosphate octahydrate
Molecular Formula
C6H27Na3O20P2
Molecular Weight
550.18 g/mol
SMILES
[O-][C@@H]([C@H]([C@@H](C(=O)COP(=O)(O)O)[O-])[O-])COP(=O)(O)O.[Na+].[Na+].[Na+].O.O.O.O.O.O.O.O
InChIKey
BUMXRRGJJDMPRT-PESUWTOCSA-K
Last Updated: 2025-09-08 00:42