Compound Q&A
How is Ertapenem sodium (CAS: 153773-82-1) typically synthesized?
Answer
Ertapenem sodium is synthesized through a multi-step process involving the use of protected 1,3-diketones, such as 2,5-dimethyl-3,6-dioxononan-1,9-dione, and 1,2,3,6-tetrahydropyridine derivatives. Catalytic hydrogenation and amidation steps are typically used to achieve high yield and selectivity, with the final product being converted to the sodium salt form.
About
CAS No
153773-82-1
English Name
Ertapenem sodium
Molecular Formula
C22H24N3NaO7S
Molecular Weight
497.5 g/mol
SMILES
CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)NC4=CC=CC(=C4)C(=O)[O-])C(=O)O)C(C)O.[Na+]
InChIKey
ZXNAQFZBWUNWJM-HRXMHBOMSA-M
Last Updated: 2025-09-08 00:42
