Compound Q&A

How is butyl 2-cyanoacetate (CAS: 5459-58-5) typically synthesized?

Answer

butyl 2-cyanoacetate
Butyl 2-cyanoacetate (CAS: 5459-58-5) is synthesized via a Grignard reaction or a cyanation process. The Grignard synthesis involves butyl bromide reacting with a cyanoacetate ion, often catalyzed by a suitable base. The cyanation process typically uses sodium cyanide in the presence of an alcohol like ethanol, followed by esterification with a carboxylic acid.

About

CAS No 5459-58-5
English Name butyl 2-cyanoacetate
Molecular Formula C7H11NO2
Molecular Weight 130.19 g/mol
SMILES CCCCOC(=O)CC#N
InChIKey BTMVHUNTONAYDX-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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