Compound Q&A
How is Ethyl (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate monohydrochloride (CAS: 651324-08-2) typically synthesized?
Answer
This compound can be synthesized via a multi-step process involving acetylation, allylation, and esterification reactions. Commonly, a Grignard reagent is used to allylate the starting cyclohexene derivative, followed by acetylation and esterification. The yield is typically around 70-80%, with high selectivity for the desired stereoisomer.
About
CAS No
651324-08-2
English Name
Ethyl (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate monohydrochloride
Molecular Formula
C26H45ClN2O4
Molecular Weight
485.1 g/mol
SMILES
CCC(CC)OC1C=C(CC(C1N(C(=O)C)C(C)(C)C)N(CC=C)CC=C)C(=O)OCC.Cl
InChIKey
PUBKCMTVXFIUCX-BAUONJEJSA-N
Last Updated: 2025-09-08 00:42
