Compound Q&A
How is Valsartan Methyl Ester (CAS: 137863-17-3) typically synthesized?
Answer
Valsartan Methyl Ester is typically synthesized by the esterification of valsartan with methanol in the presence of an acid catalyst, such as sulfuric acid. The reaction is conducted under mild conditions to achieve a high yield of approximately 90%. The product is purified by recrystallization from ethanol.
About
CAS No
137863-17-3
English Name
Valsartan Methyl Ester
Molecular Formula
C25H31N5O3
Molecular Weight
449.5 g/mol
SMILES
CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)OC
InChIKey
UJTNRXYTECQKFO-QHCPKHFHSA-N
Last Updated: 2025-09-08 00:42
