Compound Q&A

How is 3-Hydroxy-2-pyrazinecarboxamide (CAS: 55321-99-8) typically synthesized?

Answer

3-Hydroxy-2-pyrazinecarboxamide
3-Hydroxy-2-pyrazinecarboxamide (CAS: 55321-99-8) can be synthesized via a multi-step process involving the condensation of pyrazinecarboxaldehyde with hydroxyamine. The reaction is conducted in the presence of a strong base such as sodium hydroxide. The yield is typically around 70%, and the reaction is highly selective. The process requires careful control of pH and temperature to maximize yield and purity.

About

CAS No 55321-99-8
English Name 3-Hydroxy-2-pyrazinecarboxamide
Molecular Formula C5H5N3O2
Molecular Weight 139.11 g/mol
SMILES C1=CN=C(C(=O)N1)C(=O)N
InChIKey SZPBAPFUXAADQV-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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