Compound Q&A
How is Bicyclo[2.2.1]heptan-2-ol,1,7,7-trimethyl-, 2-acetate, (1R,2S,4R)-rel- (CAS: 76-49-3) typically synthesized?
Answer
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Bicyclo[2.2.1]heptan-2-ol,1,7,7-trimethyl-, 2-acetate, (1R,2S,4R)-rel- (CAS: 76-49-3) is typically synthesized via the acetylation of 1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol. The reaction is usually performed using acetic anhydride and a catalytic amount of a Lewis acid such as aluminum trichloride. The yield is around 70-80%, and the product is isolated by recrystallization from a suitable solvent.
About
CAS No
76-49-3
English Name
Bicyclo[2.2.1]heptan-2-ol,1,7,7-trimethyl-, 2-acetate, (1R,2S,4R)-rel-
Molecular Formula
C12H20O2
Molecular Weight
196.28999999999996 g/mol
SMILES
CC(=O)O[C@@H]1C[C@H]2C([C@]1(C)CC2)(C)C
InChIKey
KGEKLUUHTZCSIP-HOSYDEDBSA-N
Last Updated: 2025-09-08 00:42
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