Compound Q&A

How is 2-Bromo-1-(4-chlorophenyl)ethanone (CAS: 536-38-9) typically synthesized?

Answer

2-Bromo-1-(4-chlorophenyl)ethanone
2-Bromo-1-(4-chlorophenyl)ethanone is typically synthesized via a bromination reaction of 1-(4-chlorophenyl)ethanone. This is usually achieved using N-bromosuccinimide (NBS) in an appropriate solvent such as dichloromethane. The reaction is conducted under light or heat to achieve the desired bromination with high selectivity. The yield is generally good, around 70-80%.

About

CAS No 536-38-9
English Name 2-Bromo-1-(4-chlorophenyl)ethanone
Molecular Formula C8H6BrClO
Molecular Weight 233.49 g/mol
SMILES C1=CC(=CC=C1C(=O)CBr)Cl
InChIKey FLAYZKKEOIAALB-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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