Compound Q&A
How is 4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}benzamide (CAS: 864731-61-3) typically synthesized?
Answer
![4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}benzamide](https://static.chemtradehub.com/structs/864/864731-61-3-2e71.webp "4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}benzamide")
The compound is synthesized through a multi-step process involving the reaction of 3,5-dichlorophenyl trifluoromethyl oxazolone with a benzamide derivative. The synthesis involves the use of anhydrous solvents, mild base catalysis, and careful temperature control. The overall yield is around 60-70% and the product is isolated through column chromatography.
About
CAS No
864731-61-3
English Name
4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}benzamide
Molecular Formula
C22H17Cl2F6N3O3
Molecular Weight
556.29 g/mol
SMILES
CC1=C(C=CC(=C1)C1=NOC(C1)(C1=CC(Cl)=CC(Cl)=C1)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F
InChIKey
MLBZKOGAMRTSKP-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
![4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}benzamide — Shandong Mayo Huahui Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce79492b2de6e8e95a4693/67ce79492b2de6e8e95a4693-logo.webp){kind=logo}
![4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}benzamide — Jiangsu Laineng Environmental Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce706f2b2de6e8e95a45d7/67ce706f2b2de6e8e95a45d7-logo.webp){kind=logo}
![4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}benzamide — SkyFlu (Shanghai) Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cde93057537e5c8069af3f/67cde93057537e5c8069af3f-logo.webp){kind=logo}