Compound Q&A

How is 4-Aminobenzenesulfonic acid (CAS: 121-57-3) typically synthesized?

Answer

4-Aminobenzenesulfonic acid
4-Aminobenzenesulfonic acid can be synthesized by the sulfonation of 4-aminobenzoic acid. This process involves treating 4-aminobenzoic acid with fuming sulfuric acid in the presence of a catalyst like pyridine. The reaction is typically carried out at elevated temperatures to improve yield and selectivity. The overall yield can range from 70% to 80% depending on reaction conditions and purification methods.

About

CAS No 121-57-3
English Name 4-Aminobenzenesulfonic acid
Molecular Formula C6H7NO3S
Molecular Weight 173.19 g/mol
SMILES Nc1ccc(cc1)S(=O)(=O)O
InChIKey HVBSAKJJOYLTQU-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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