Compound Q&A

How is 2-Thienylacetonitrile (CAS: 20893-30-5) typically synthesized?

Answer

2-Thienylacetonitrile
2-Thienylacetonitrile is commonly synthesized via the reaction of thiophene and acetonitrile in the presence of a base. This method involves treating thiophene with acetonitrile in an organic solvent such as toluene or DMF with a base like potassium tert-butoxide. The reaction is exothermic and should be carried out under stirring conditions. The yield is typically around 70-80%, with good selectivity for the desired product.

About

CAS No 20893-30-5
English Name 2-Thienylacetonitrile
Molecular Formula C6H5NS
Molecular Weight 17.03 g/mol
SMILES C1=CSC(=C1)CC#N
InChIKey CLSHQIDDCJTHAJ-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

Related Q&A

Compound Q&A

What are the physical and chemical properties of 2-Thienylacetonitrile (CAS: 20893-30-5)?

2-Thienylacetonitrile is a colorless to light yellow liquid with a molecular weight of approximately...

Compound Q&A

What industries use 2-Thienylacetonitrile (CAS: 20893-30-5)?

2-Thienylacetonitrile is used in various industries due to its chemical reactivity and functional gr...

Compound Q&A

What precautions should be taken when handling 2-Thienylacetonitrile (CAS: 20893-30-5)?

When handling 2-Thienylacetonitrile, it is important to use appropriate personal protective equipmen...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...